Patient Education: Addyi (Flibanserin)

What is Addyi?

Addyi is a prescription medication used to treat hypoactive sexual desire disorder (HSDD) in premenopausal women. HSDD is characterized by a persistent lack of sexual desire that is distressing and is not due to:

• Medical or mental health issues
• Relationship problems
• Medications or substance use

Important Note: Addyi is not intended for use in menopausal women, men, or for improving sexual performance.

How Should I Take Addyi?

• Dosage: Take 1 tablet daily at bedtime.
• Timing: Only take Addyi at bedtime. Taking it at other times can increase the risk of severe side effects such as low blood pressure and fainting.
• Missed Dose: If you miss a dose, take your next dose at bedtime the following day. Do not take Addyi in the morning or double up on doses.

Important Safety Information

• Alcohol: Your risk of severe low blood pressure and fainting is increased if you:
  • Drink alcohol close to when you take Addyi.
  • Wait at least 2 hours after consuming 1-2 standard alcoholic drinks before taking Addyi. Examples of standard drinks:
    • 12-ounce beer
    • 5 ounces of wine
    • 1.5 ounces of distilled spirits
  • If you consume 3 or more drinks, skip your Addyi dose that evening.
  • After taking Addyi, do not drink alcohol until the next day.
• Drug Interactions: Do not take Addyi with certain medications as it can lead to severe low blood pressure and fainting. Inform your doctor if you are taking:
  • Medicines for HIV (e.g., ritonavir, atazanavir)
  • Fungal infection medications (e.g., fluconazole)
  • Certain antibiotics (e.g., erythromycin)
  • Other specified medications (see full list if necessary).
• Liver Problems: Do not take Addyi if you have liver issues.

Side Effects

• Common side effects include:
  • Dizziness
  • Nausea
  • Tiredness
  • Difficulty sleeping
  • Dry mouth
• Serious Side Effects: Call your doctor if you experience:
  • Lightheadedness or dizziness—lie down immediately. If symptoms persist or if you feel faint, seek emergency help.
  • If you faint, inform your doctor as soon as possible.

Precautions Before Taking Addyi

Inform your doctor if you have:

• A history of alcohol or drug abuse.
• Mental health issues (e.g., depression).
• Low blood pressure or related conditions.
• Plans to become pregnant or if breastfeeding.

What to Avoid While Taking Addyi

• Do not drink alcohol close to your dose.
• Do not drive or operate machinery for at least 6 hours after taking Addyi until you know how it affects you.
• Avoid grapefruit juice and certain herbal supplements (e.g., St. John’s Wort) unless cleared by your doctor.

Storage

• Store Addyi at room temperature (68°F to 77°F or 20°C to 25°C).
• Keep out of reach of children.

General Information

Medicines are sometimes prescribed for purposes other than those listed. Do not share Addyi with others, and use it only as prescribed by your healthcare provider.

For more information, you can visit www.ADDYI.com or call 1-844-PINK-PILL (1-844-746-5745).

For further assistance or inquiries, please contact us at help@persimmon.life. We are available to provide any additional information you may need.