Pre & Post Treatment Care Instructions
Standard | PDRN | PRP
Please inform your provider before treatment if any of the following apply to you:
Open wounds, active sores, or irritated skin at the treatment area
Active skin cancer
Allergy to stainless steel or anesthetic ingredients (benzocaine, lidocaine, tetracaine)
Bleeding or clotting disorders
Currently pregnant or nursing
Current or recent use of Accutane (isotretinoin)
Keloid scarring
Active infection or fever
Use the timeline below to prepare for your appointment:
7 Days Before
Avoid chemical peels, waxing, electrolysis, laser treatments
Discontinue blood thinners (aspirin, NSAIDs, vitamin E, fish oil, ginkgo) — if approved by your physician
Avoid excessive sun exposure
3 Days Before
Discontinue retinoids, tretinoin, AHAs, BHAs, glycolic/salicylic acids, and other exfoliating agents
If you have a history of herpes/cold sores, begin antiviral medication (contact your PCP for a prescription)
Minimize alcohol consumption
Day of Treatment
Arrive with a clean face — no makeup or skincare products
Drink plenty of fluids
If receiving PRP, do not come fasting — eat a normal meal beforehand
Shave the treatment area 1–2 days before your appointment if applicable.
Avoid active tanning or sunburn before treatment.
Disclose all current medications, supplements, and relevant medical history to your provider.
If you are taking blood thinners or anticoagulants (e.g., Warfarin, Plavix, Heparin), consult your physician before stopping them. Do not discontinue prescription medications without medical guidance.
Arrive with a completely clean face — no makeup, moisturizer, or skincare products.
If you are receiving PRP microneedling, eat a normal meal beforehand — do not come fasting.
Drink plenty of fluids throughout the day.
Let your provider know if you feel unwell, have a fever, or have developed any skin irritation since booking.
Follow the timeline below for your recovery:
First 24 Hours
No makeup, cleansers, lotions, or skincare products on treated area
Rinse with cool water only if needed
Apply post-care ointment at bedtime and at other times as needed
No exercise, sweating, or activities that increase blood flow
Strict sun avoidance — no sunscreen directly after treatment
Use a clean pillowcase
Days 2–3
Apply post-care ointment in place of your regular moisturizer
Reapply post-care ointment as needed
Begin using mineral sunscreen (SPF 30+)
Continue to avoid exercise and sun exposure
Continue to avoid exfoliating products
Avoid saunas, swimming, and hot tubs
Days 4–7
You may return to your regular skincare routine (unless skin is still sensitive)
Continue to avoid corrective/exfoliating products if you have any sensitivity
Continue sun avoidance and daily SPF 30+
Avoid aggressive exfoliating agents for the full 7 days
Redness and warmth (like a moderate sunburn) for 24–72 hours is completely normal.
Mild swelling, skin tightness, or tenderness at the treatment site.
Pinpoint bruising (tiny red/purple dots under the skin surface) — this resolves within 3–14 days.
Skin flaking or peeling may occur in days 2–5. Do not pick or peel the skin.
A burning or itching sensation is common for the first 24 hours. After 24 hours, a thin layer of hydrocortisone mixed with a mild moisturizer may help relieve itchiness.
Full recovery typically takes 1–2 weeks. Collagen production continues for up to 6 weeks after treatment.
Absence of visible peeling does not mean treatment was ineffective — your skin is still repairing and producing collagen internally.
If you received PRP or PDRN, leave any residual serum on your skin until your nighttime skincare routine — do not rinse it off immediately after treatment.
Your provider will apply a post-procedure face mask before you leave. Leave it on for a minimum of 10–15 minutes after arriving home.
Avoid vigorous exercise for 48 hours post-treatment.
Avoid NSAIDs (Advil, Motrin, Ibuprofen, Naproxen) for 48 hours after treatment — Tylenol (acetaminophen) is acceptable for pain relief.
⚠ Contact Your Provider Immediately If You Experience:
Drainage or pus from the treated area
Increasing warmth, significant swelling, or redness that worsens after 48 hours
Fever of 101.5°F or higher
Severe pain that is unresponsive to over-the-counter pain relievers
Vision changes, difficulty breathing, or signs of allergic reaction
Cold sore or herpes outbreak at or near the treatment site
For Best Results
A series of 3 or more treatments spaced 3–6 weeks apart yields the best outcomes. Ask your provider about the right schedule for your skin concerns.
Questions? Contact your Persimmon provider or message us through the Persimmon app.
This page may contain images of models and not actual patients